| | Name | Team | GP | Pass Yds | Pass TDs | Pass Ints | Rush Yds | Rush TDs | Points |
|---|
| 1. | Drew Brees | Saints | 16 | 4,158.0 | 29.6 | 15.2 | 32.0 | 0.2 | 317.7 |
| 2. | Tom Brady | Patriots | 16 | 4,068.7 | 29.6 | 13.5 | -12.1 | 0.0 | 312.0 |
| 3. | Peyton Manning | Colts | 16 | 3,993.1 | 27.9 | 14.9 | 14.4 | 0.1 | 299.8 |
| 4. | Philip Rivers | Chargers | 16 | 3,975.5 | 26.4 | 15.3 | -11.3 | 0.0 | 286.0 |
| 5. | Aaron Rodgers | Packers | 15 | 3,736.7 | 23.4 | 13.9 | 113.9 | 0.5 | 276.5 |
| 6. | Brett Favre | Vikings | 16 | 3,313.1 | 25.1 | 13.8 | -13.5 | 0.0 | 254.4 |
| 7. | Jay Cutler | Bears | 16 | 3,644.4 | 21.3 | 17.7 | 130.5 | 0.5 | 254.4 |
| 8. | Kurt Warner | Cardinals | 13 | 3,348.1 | 24.0 | 11.8 | -10.8 | 0.0 | 253.5 |
| 9. | Tony Romo | Cowboys | 15 | 3,630.7 | 21.8 | 18.5 | 68.6 | 0.3 | 247.9 |
| 10. | Matt Ryan | Falcons | 16 | 3,044.8 | 22.1 | 11.6 | 46.7 | 0.2 | 237.6 |
| 11. | Donovan McNabb | Eagles | 14 | 3,246.6 | 20.5 | 11.5 | 30.9 | 0.2 | 233.7 |
| 12. | Trent Edwards | Bills | 14 | 3,290.5 | 20.8 | 18.2 | 79.8 | 0.4 | 230.2 |
| 13. | Joe Flacco | Ravens | 16 | 3,036.2 | 19.3 | 12.3 | 131.0 | 0.6 | 229.7 |
| 14. | Ben Roethlisberger | Steelers | 16 | 3,205.0 | 19.2 | 14.9 | 44.6 | 0.2 | 219.5 |
| | Name | Team | GP | Pass Yds | Pass TDs | Pass Ints | Rush Yds | Rush TDs | Points |
|---|
| 15. | David Garrard | Jaguars | 13 | 2,674.9 | 15.5 | 10.7 | 309.9 | 1.3 | 217.1 |
| 16. | Carson Palmer | Bengals | 14 | 2,975.2 | 19.0 | 10.4 | 1.6 | 0.0 | 212.6 |
| 17. | Matt Schaub | Texans | 11 | 2,855.2 | 19.7 | 12.6 | 38.5 | 0.2 | 212.6 |
| 18. | Shaun Hill | 49ers | 14 | 2,750.0 | 17.6 | 11.1 | 84.8 | 0.4 | 204.3 |
| 19. | Eli Manning | Giants | 16 | 2,807.2 | 18.6 | 12.1 | 5.0 | 0.1 | 200.6 |
| 20. | Mark Sanchez | Jets | 16 | 2,787.8 | 18.1 | 16.1 | 34.0 | 0.2 | 192.5 |
| 21. | Kyle Orton | Broncos | 12 | 2,838.4 | 16.6 | 13.9 | 26.9 | 0.1 | 188.5 |
| 22. | Matthew Stafford | Lions | 14 | 2,805.0 | 16.5 | 14.7 | 21.3 | 0.1 | 184.6 |
| 23. | Kerry Collins | Titans | 13 | 2,542.5 | 15.9 | 8.2 | 15.1 | 0.1 | 182.4 |
| 24. | Jason Campbell | Redskins | 14 | 2,294.3 | 13.5 | 8.9 | 195.0 | 0.9 | 180.0 |
| 25. | Matt Cassel | Chiefs | 13 | 2,326.0 | 12.6 | 11.1 | 180.3 | 0.8 | 169.3 |
| 26. | Matt Hasselbeck | Seahawks | 13 | 2,411.5 | 14.9 | 12.0 | 33.8 | 0.2 | 166.1 |
| 27. | Chad Pennington | Dolphins | 11 | 2,176.1 | 14.0 | 6.2 | 20.2 | 0.2 | 161.7 |
| 28. | Marc Bulger | Rams | 13 | 2,439.1 | 14.0 | 11.9 | 11.2 | 0.0 | 159.1 |
| 29. | Byron Leftwich | Buccaneers | 12 | 2,135.0 | 13.2 | 7.3 | 12.5 | 0.1 | 151.4 |
| | Name | Team | GP | Pass Yds | Pass TDs | Pass Ints | Rush Yds | Rush TDs | Points |
|---|
| 30. | Jake Delhomme | Panthers | 13 | 2,252.4 | 13.9 | 11.4 | 6.1 | 0.1 | 151.3 |
| 31. | Brady Quinn | Browns | 12 | 2,160.5 | 13.5 | 9.6 | 18.0 | 0.1 | 150.4 |
| 32. | JaMarcus Russell | Raiders | 11 | 2,126.6 | 13.1 | 9.7 | 21.7 | 0.1 | 147.0 |
| 33. | Dan Orlovsky | Texans | 13 | 1,171.2 | 6.9 | 7.1 | 10.5 | 0.1 | 75.4 |
| 34. | Chris Simms | Broncos | 8 | 1,015.4 | 6.8 | 3.8 | -1.1 | 0.0 | 73.7 |
| 35. | Jeff Garcia | Raiders | 6 | 751.3 | 4.8 | 2.6 | 21.5 | 0.1 | 56.2 |
| 36. | Brian St. Pierre | Cardinals | 3 | 720.6 | 5.1 | 3.0 | -2.5 | 0.0 | 53.4 |
| 37. | Derek Anderson | Browns | 6 | 716.9 | 4.7 | 3.5 | 7.8 | 0.0 | 51.0 |
| 38. | Pat White | Dolphins | 13 | 195.0 | 1.1 | 0.5 | 241.1 | 1.3 | 45.0 |
| 39. | Vince Young | Titans | 10 | 466.6 | 2.9 | 3.0 | 80.3 | 0.5 | 41.0 |
| 40. | Tyler Thigpen | Chiefs | 6 | 551.0 | 3.3 | 2.7 | 34.8 | 0.2 | 40.7 |
| 41. | Todd Bouman | Jaguars | 10 | 672.2 | 3.8 | 4.6 | -0.7 | 0.0 | 40.5 |
| 42. | Chad Henne | Dolphins | 3 | 591.4 | 3.3 | 1.9 | -1.9 | 0.0 | 39.7 |
| 43. | Josh McCown | Panthers | 4 | 547.6 | 3.9 | 3.1 | 0.9 | 0.0 | 39.0 |
| 44. | Michael Vick | Eagles | 13 | 191.7 | 1.0 | 0.6 | 200.4 | 0.9 | 37.5 |
| | Name | Team | GP | Pass Yds | Pass TDs | Pass Ints | Rush Yds | Rush TDs | Points |
|---|
| 45. | Alex Smith | 49ers | 9 | 394.6 | 3.1 | 1.7 | 13.4 | 0.1 | 32.6 |
| 46. | Kyle Boller | Rams | 13 | 538.0 | 2.9 | 3.4 | -0.5 | 0.0 | 31.9 |
| 47. | Ryan Fitzpatrick | Bills | 16 | 417.0 | 2.4 | 1.7 | 30.2 | 0.1 | 31.4 |
| 48. | Seneca Wallace | Seahawks | 6 | 354.8 | 2.3 | 1.2 | 17.2 | 0.1 | 27.7 |
| 49. | Luke McCown | Buccaneers | 3 | 373.3 | 2.5 | 1.6 | 4.7 | 0.0 | 27.3 |
| 50. | Daunte Culpepper | Lions | 10 | 404.6 | 2.4 | 2.1 | 8.8 | 0.0 | 27.1 |
| 51. | J.T. O'Sullivan | Bengals | 13 | 369.6 | 2.1 | 2.4 | 12.6 | 0.0 | 24.1 |
| 52. | Josh Freeman | Buccaneers | 2 | 343.1 | 2.3 | 2.0 | 7.9 | 0.0 | 24.1 |
| 53. | Jon Kitna | Cowboys | 16 | 264.0 | 1.8 | 1.4 | 2.9 | 0.0 | 19.1 |
| 54. | Matt Flynn | Packers | 15 | 264.8 | 1.6 | 1.3 | -0.6 | 0.0 | 17.3 |
| 55. | Bruce Gradkowski | Raiders | 3 | 221.8 | 1.8 | 1.2 | -0.4 | 0.0 | 17.1 |
| 56. | Todd Collins | Redskins | 2 | 195.3 | 1.4 | 0.8 | -0.9 | 0.0 | 14.1 |
| 57. | Mike Teel | Seahawks | 1 | 176.2 | 0.9 | 0.9 | -0.1 | 0.0 | 10.8 |
| 58. | Colt Brennan | Redskins | 2 | 162.1 | 0.7 | 1.4 | -0.3 | 0.0 | 8.0 |
| 59. | Billy Volek | Chargers | 16 | 34.5 | 0.2 | 0.2 | 0.1 | 0.0 | 2.1 |
| | Name | Team | GP | Pass Yds | Pass TDs | Pass Ints | Rush Yds | Rush TDs | Points |
|---|
| 60. | Andrew Walter | Patriots | 16 | 12.1 | 0.1 | 0.1 | 0.4 | 0.0 | 0.8 |
| 61. | Mark Brunell | Saints | 16 | 10.2 | 0.1 | 0.1 | 0.0 | 0.0 | 0.7 |
| 62. | Tom Brandstater | Broncos | 12 | 11.7 | 0.1 | 0.1 | 0.0 | 0.0 | 0.7 |
| 63. | Caleb Hanie | Bears | 16 | 4.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.2 |
| 64. | Alex Brink | Texans | 3 | 3.4 | 0.0 | 0.0 | -0.0 | 0.0 | 0.2 |
| 65. | Rex Grossman | Texans | 5 | 3.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.2 |