A few seasons ago I did. My gameplan usually has the QB rushing at 8% and that usually gets about 300 yards a season.
Order of effectiveness for a running QB in my experience is Trips, Pro, SG, ND (I haven't used the other ones but SG is only effective because people default their gameplans to always pass. Trips and Pro are about equal it in. Right now there is a QB in Stagg (Yale) who has about 500 yards rushing halfway through the season. That coach runs trips exclusively.