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| The 2001 Buffalo Bills roster is below. Clicking on a tab heading will display the specified set of statistics. All columns may be sorted by clicking the column name. Clicking on an individual player will display the player's career statistics including his time with the 2001 Buffalo Bills. |
| Name | Pos | GP | Tackles | Sacks | Int |
|---|---|---|---|---|---|
| '01 Jay Foreman | LB | 16 | 69 | 2.5 | 0 |
| '01 Antoine Winfield | CB | 16 | 69 | 0 | 2 |
| '01 Keith Newman | LB | 16 | 63 | 3.5 | 0 |
| '01 Nate Clements | CB | 16 | 56 | 1 | 3 |
| '01 Brandon Spoon | LB | 15 | 45 | 0 | 2 |
| '01 Pat Williams | DT | 13 | 41 | 1.5 | 0 |
| '01 Ken Irvin | DB | 14 | 33 | 0 | 1 |
| '01 Raion Hill | DB | 15 | 29 | 0 | 0 |
| '01 Bryce Fisher | DT | 15 | 27 | 6.5 | 0 |
| '01 Keion Carpenter | S | 15 | 24 | 0 | 0 |
| '01 Pierson Prioleau | S | 8 | 23 | 1 | 0 |
| '01 Phil Hansen | DL | 12 | 22 | 2.5 | 1 |
| '01 Aaron Schobel | DE | 16 | 22 | 2 | 0 |
| '01 Travares Tillman | DB | 12 | 22 | 0 | 1 |
| '01 Tyrone Robertson | DT | 12 | 19 | 2 | 0 |
| '01 Shawn Price | DE | 10 | 18 | 2 | 0 |
| '01 Erik Flowers | DE | 15 | 15 | 2.5 | 0 |
| '01 Dashon Polk | LB | 16 | 13 | 0 | 0 |
| '01 Kendrick Office | DE | 9 | 11 | 3 | 0 |
| '01 Kenyatta Wright | LB | 8 | 11 | 1.5 | 0 |
| '01 Leif Larsen | DT | 10 | 11 | 1 | 0 |
| '01 Chris Watson | CB | 12 | 10 | 0 | 1 |
| '01 Lance Brown | DB | 15 | 7 | 0 | 0 |
| '01 Ron Edwards | DT | 11 | 7 | 0 | 0 |
| '01 Fred Jones | LB | 15 | 0 | 0.5 | 0 |
| '01 Tony Driver | S | 5 | 0 | 0 | 0 |
| '01 Sam Cowart | LB | 1 | 0 | 0 | 0 |
| '01 Jimmy Robinson | LB | 0 | 0 | 0 | 0 |
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