I maintain all my usual settings. My starters play the first 4 games and then are rested for the duration of ST; 2 or 3 more "platoons" of position players come in behind them and play 4-7 games each. I maintain a 6-9 man rotation, make all other pitchers SuA, and rest any bullpen pitcher who hits 5 IP.
As long as pitchers and position players don't lose DUR, ST, or HE over the offseason and have to "rebuild it" during ST, I see no reason to do the extra work to mimic real ST.