With the state of the game right now, there IS no right or wrong answer. Long term, zharkins is right: if you're giving up a huge talent advantage, you're gonna get torched. You can only recruit to eliminate the advantage. Short term, the only thing you can do is alter your game plan, but that cuts both ways: If you go more aggressive, you're more likely to get INTs, but more likely to get burned long. I like this option when I have DBs "better" (whatever that means...) than my oponents WRs. If you go more conservative, you're less likely to give up the long passes, but will tend to give up more completions, and won't have as many INTs. This is a good option if your DBs aren't as good as his WRs. Note that for the conservative option, you'll need decent stamina in your DBs, otherwise that AC recruited freshman will end up on the field when you're in the red zone. The "Always Pass" defense is also an option, but I wouldn't recommend it unless your opponent doesn't actually have any RBs, and even then it might backfire (I remember a game where my QB scrambled for two 60+ yd TDs. Don't let that happen to you.).