For all of the positions requiring some skill to play (C,2B,3B,SS,CF), I set a target of 2. To make sure I draft enough potential innings pitched, I set SP to 7 and RP to 3 leaving an Any of 5. I set my ratings threshold to none as I want to draft the best possible player for the first few rounds, which my ANY of 5 allows for. Meanwhile for the minor league fodder, my targets make sure I get all the positions filled out to field a team.