Hey - I am in a situation where I have 2 young QBs.  One is  RS FR, the other a RS SO.  I think the FR has slightly better attributes, but the SO has had an additional year in the system.

Thinking of playing them both based on fatigue (ie fresh or fairly fresh) and wonder if this is a valid strategy.  I'm hoping two nearly equal QBs who are never tired will offset their young age a little bit :)

Your RS Freshman is hands down the better QB.  I'd start him and do what you suggest above.  The soph is good, so set them to FRESH and turn em loose

+1

I played my last exhibition game and the #1 guy got all the snaps.  The #2 guy had 2 passing attempts.  Was hoping "fresh" would give more parity, but apparently QBs dont tire too much out there........

No matter what settings you use, you are not going to get more than 15-20% for your #2 guy.  If you want to increase his playing time you will need to let him play in 2H of some blowouts.  I would not worry about #2.  Best overall approach is to keep your best players on the field.  That is your best chance to win.