I think it wil be a very balanced league depending on how the teams are managed. If the fatigue teams play it just to win then I think they have an advantage (using the classic fatigue strategy). However, if the fatigue teams play it straight and try to win they should be able to keep their whole staff in the 70% range, at worst. From my small sample of two test leagues pitchers with around a .220 OAV, WHIP of 0.95 and BB/9 of 1.00 will finish up around .275/1.35/1.90 depending on ballparks and normalizations; which is very close to the stat lines the bad teams are starting with (though my team has a much better starting line than the one above, but they'll also be pitching into the 70% range). I expect the fatigue teams to jump out to a quick lead and then fade down the stretch, but they should still be just competitive enough.