When you say you click on the "Default" button, do you mean "Use Default" on the right side of the schedule screen? That takes you to the same page as "Match Tactics". So:
Make changes with the Edit button.
Save changes, bottom right.
Go back to Match Tactics, make sure the graphic of your lineup displays the players you want.
If that is the only formation you're using, you're good to go.
If you have more than one formation in the system, be sure you're in the one you want (from the dropdown).
On the left above the formation name, there's a circle. If it's green and it says Default, it's your default. If it's not, it's not your default and that's why your formation reverts to whatever other setting you have. Hover over it and it says click to set as Default. When it's green you're good.
And if you've got formations set up that you don't want to use, delete them.