Does it matter if your best guys are at offensive tackle? In real life I would put your elite OL on the ends to protect against the pass rush. Does it matter in this game?
Yes, it matters greatly actually. An outside running play is calculated differently than an inside running play. The Offense and Defensive players involved in the calculation are different. Please take a look at Dev Chats for the exact players involved.
Much of it is common sense. For example, if you are running inside...you want your best run blocking OL at the G, C and G locations.
Here is the rub. Since players substitute in the game based on stamina, many times it is hard to control the location of your OL. As a result, most coaches take a look at the whole OL since they find it difficult to manage substitutions. It takes a well prepared gameplan to insure that your best 3 OL are G, C, G on a random inside running play in the middle of the fourth quarter.
Hope this make sense.
nitros (James)