I disagree that, defensively, 35 speed will make up for 16 ath/25 def in a man def.
On the other hand, there's no way you can play a PG with 50/60 ath/spd and expect to be elite in man. I don't think either are capable of playing PG at an elite level in D3, but I would go player 2, no question, given his spd/per advantage.