Do you know - when you set your defense (man to man) to 'double team' when 'leading scorer', does this mean:
a) When the player is the leading scorer for that team that is currently in the game
          or
b) When the player is the leading scorer for that team overall

For example, 'Bob' has 20 points, and 'Brian' has 15 points.  'Bob' goes to the bench for a break, but 'Brian' remains in the game.  If 'Brian' is set to 'double team when leading scorer', will he now be double teamed since 'Bob' is out of the game?

It is option A but only if the double team can be done (ex. If you set Player A and Player B to "Always" double team and Player C to "If Leading Scorer" and all 3 were on the floor and C was the leading scorer, then nobody would be double teamed).

Your example is correct in how it would occur.

I'm not so sure nobody would be double teamed in that scneario buddy