With all the picks in, here's my crack at division alignment, very similar to last season, but shifting the Braves west instead of the Reds. Both have played in the west in real life. Brewers go to the AL Central, where they have some experience.
NL East: Marlins, Mets, Phillies, Expos/Nationals
NL Central: Reds, Pirates, Cubs, Cardinals
NL West: Braves, Dodgers, Giants, Padres
AL East: Yankees, Red Sox, Orioles, Blue Jays
AL Central: Brewers, Twins, Tigers, Indians
AL West: Astros, Diamondbacks, Athletics, Mariners