Following boogerlips poll: I play in Wrigley or AFC (+2 each) and the only pitcher that ever comes in fatigued is my mop, who may or may not be fatigued, but I allow him to pitch fatigued, and always target 1,200 IP... but, as I posted back on page two, when you factor in AAA and your 10%, 1,150 isn't really much of a stretch either. The only reason to go to 1,250 for the minimum is to alter ballpark usage. 1,150 would satisfy the answer to the question of curbing fatigue strategies, and 900 would protect newbies from themselves.
The flaws in the system can and will still be manipulated even if the minimum is set 1,400 IP, which is why I questioned the introduction of the minimum at all, especially with the advent of a fix to the flawed system coming in short order.
[EDITED for readability]