I'm not convinced that wide open immigration policies are particularly beneficial economically. I think given the current economic state of the nation it's basically an economic net neutral. I understand why many smaller countries feel the need to restrict immigration to highly educated/skilled persons, but I think the arguments for such policies don't currently apply here. I just don't see a strong argument that adding a large number of low-education immigrants is going to improve economic status for the current population. That said, I'm generally in favor of making immigration much easier, and part of that includes finding a way of doing a better job of informing potential immigrants of how the new system works. I've also said in the past that I'm not into a policy of pure forgiveness for undocumented entries, but I also don't think deportation of people with no other criminal background is a humanitarian win or particularly effective. I've suggested in the past that undocumented families be subject to either a purpose-built family incarceration center with educational options for children, or a single adult be subject to minimum-security incarceration, for a term of ~6 months during which they would be helped with filling out and processing paperwork for resident alien status. That way there's still a meaningful disincentive to avoid proper documentation, but without generating a humanitarian crisis. I also think resident alien status needs to be less closely linked to work. It's really scary living in a reality where losing your job could basically make your family "illegal" overnight. Nobody whose done everything the right way should need to live with that kind of insecurity and fear.
For myself, my #1 issue by far remains balanced economic growth. If any party would draw up a realistic plan (IE, not what the Libertarians are advancing) to balance the Federal budget in 10-20 years, which feels like the shortest even quasi-reasonable horizon, I would back that party in an instant. It seems plausible - phased reduction in military spending, cap entitlements, raise taxes on the top 15-20% (and yes, that does include me). I just don't see that happening in the next few election cycles, so I'm focused more on economic policy than fiscal policy.