I'm not sure that changing distro, depth charts, etc for every opponent is a good idea just for changes sake. I was going to respond to the poll, but I'm not sure now what my answer is, based on the question parameters. I am now running press on most of my teams, so changing for defensive match-ups is moot. Most of my players are playing at their optimal positions already - my PG is my PG generally, since he is the best passer, etc. I wouldn't move him to 2 guard and start the weaker PG skilled SG instead just because the opp plays man and his PG is weaker defensively unless I was convinced making the change would be a + that would offset the lack of PG skills., etc. I might be able to slide bigs around, or maybe make the SF play PF, etc if that works out, but it often doesn't make sense. So I look at all those factors for most games, but I may only change the +/- def setting or something minor. Even if I don't make changes that is still gameplanning, right?
Over changing things all the time is often not optimal. I am frequently guilty of tunnel vision where I focus on changing some aspect for a perceived benefit while failing to recognize the negatives to said change, which frequently outweigh my perceived advantage...