I think in many ways, coming up with a 'blueprint' limits you. The ratings all work together. I believe that just about any pitcher that is of BL quality can be used - somewhere - effectively. You just need to find what it is.
I have
Pedro Rodriguez (R) on my Hunter team. Great pitcher, but his low stamina doesn't allow him to go too many innings. The previous owner used him as a closer. During the season, I made him my LRA with inning available set to 'any'. If my hairy SPs get to the 5th then he'll put in an inning or two. If the SP falls apart early, he usually stops the threat. I also use him as a spot starter. In the playoffs I moved Rodriguez to starter because short term results become WAY more important in the playoffs. But that strategy allowed me to win a title last year and get back to the playoffs this season.
Donn Clark (P) got me 28 wins as a SP in two seasons in season 23 and 24 of Gleemanworld2 despite splits of 51/46. He just happened to be very good in almost every other rating. And his success wasn't just because of SWB. He killed it on the road too.
Peter Vanguri - P is a similar pitcher, but I have him in LR. His splits suck too, but he's (IMO) overpitched those ratings and won 26 games the last two seasons. These types of pitchers for other owners seem to almost always get hammered.
So I don't think there is an easily defined answer to any of it. You just have to be willing to move pitchers around, try them in different roles. Increase/reduce pitch counts and increase/reduce pull ratings. Give them innings. read the play by play in those box scores. You'd be surprised what you can get out of them.