In my opinion, you can build your team to run uptempo, to the point where as long as the following conditions are right, it is always a viable option:
1. Enough stamina. Presuming a full 12-man team, mid 70s for zone, high 70s for man, low 80s for press, mid 80s for FB/press is an ok rule of thumb.
2. A speed/ball-handling advantage over your opponent. Most important for guards, but it matters for everyone with distribution. Consider passing too, especially if your opponent presses. You have to limit turnovers. Uptempo increases your turnovers, so you’ll want to start with an advantage to mitigate that negative so it doesn’t become a deficit.
3. Solid defense, no glaring weak links. Running uptempo increases fatigue, which affects defense. Tired defenders are more likely to foul. So if you have guys prone to foul trouble under normal settings, think twice before moving to uptempo.
If those three conditions are met, I consider uptempo primarily if I am confident I have the better team, and want more possessions to reduce statistical variability; and secondarily if my opponent has a short bench, or some other fatigue-related deficit I think uptempo might exploit.