Yep, agree with Mully. FCP + tempo could bring a 100 stamina guy down in minutes to the low 30's - combine that with late game settings if you're winning or losing by a lot, and he may just get benched for that.
Also, not 100% sure on it, but I swear there was an old forum post that talked about how the only way to get players consistently above 35 minutes a game is with target minutes or setting a kid to foul trouble only in fatigue settings. Even a 100 stamina kid with all other things perfect will wind up with 33-34 minutes a game, max, and that's potentially set to very tired. (this may just be a forum myth though or something that was patched when moving from 1.0 to 2.0 or 2.0 to 3.0).