FYI - I asked thejuice6 via site-mail about multiple teams in one division. He basically said this should be avoided at all costs, which means the last few picks might be forced due to this restriction. Those with multiple teams should be safe unless one or more of those teams is picking near the end of the draft. I will end up with 10 or 11 teams, which could be problematic without this "must-be-in-separate-divisions" mandate.
If I end up with 11 teams, 6 teams will be in one league, which means each of my six selections must fall in a different division. Obviously, when I am choosing my 2nd, 3rd, 4th teams, I will pick a team from a different division. At some point as each division starts to fill up, there will be a situation where the last spot must be reserved for one of my teams.
Here is an extreme example to illustrate the point. Let's say I have 6 teams in League 1. I therefore have to have one team in each of the six divisions. I have draft pick numbers 1, 5, 10, 12, 18, 24. I select a team in the NL East (1901-1910) with pick #1. The next three people each choose a team in the NL West (1921-1930). Since I must have a team in each division, the last spot in the NL West is reserved for one of my picks - nobody else can pick from this division (obviously, I would not be forced to use my #5 pick for the fourth team in a division).
This could easily happen to somebody else with multiple teams especially if they have a very late pick. Let's say nocomm999 has 3 teams in League 1. He has already selected a team in the NL East and AL Central. Now there are two picks left, including nocomm999 who has the last pick. The two divisions left are AL West and AL Central. The person picking 2nd-to-last must take a team in the AL Central so nocomm999 doesn't have two teams in that division.
It should be pretty easy to keep track of potential conflicts as the draft progresses.