Good point, Bastan. I know I have had teams in the past that seemed to be more successful in SIM games than LIVE (course that may be because I am a terrible LIVE manager), but I wouldn't think SIM players would intentionally draft good SIM players, if that is even possible. I personally think that playing more LIVE games can help you during the course of the season because you can manipulate subs, pitching, etc.....
I have played in just about all the popular LIVE leagues at least once or twice, and frankly, you have to be pretty committed and put away a decent block of time to play in USA, UNO, etc....to manage your team with success....
I have just recently been playing SIM theme leagues, and there are some really good players and nice guys out there that just don't get into LIVE for whatever reason. There are quite a few leagues on the SIM side open as well, but if you set high LIVE minimums, you are going to see the same 15-16 die hard LIVE players and no new blood.