Certainly not up there at the top of the priority list at the point. However, I didn't think it would be a bad idea to look at, in the future in having timeout settings on your team page. I know there are times where some of my players have gone past that "fairly fresh" point under the fatigue settings before there was an opportunity to sub. Maybe just give your whole team a much needed rest. Especially teams that use the uptempo/FCP option.
For instance, you could have your settings adjusted to save your timeouts toward the end of the game, or use them sporadically throughout the game. You could have always at the end of the game, most of the time, balanced, some of the time and never. Thoughts?