Should I use the standard computer recommendations for pitch count? if not, what guidelines should I use to adjust them?

Start with the recs, adjust accordingly up or down based on your observations.

The biggest concern I had (have) with PCs in HBD is predicting when a pitcher hits his in-game fatigue point. In SLB Elbirdo came up with an exact way of knowing how many pitches a pitcher could throw per game before being penalized. Here we only have 'stamina'. Just guessing, I figured a 100 stamina pitcher would be good for 130 pitches, and that it goes down linearly from there (a 50 stamina pitcher would be good for 65 pitches). The interesting thing about my guess is that it lines up pretty closely with the recommended target count. The max count is usually a lot higher, but based on my observations in SLB, the target count is suggestive of their in-game fatigue point. Hope that helps...