One of the fatigue settings is foul trouble only...does this mean the player will only be taken out if he's in foul trouble or only will play if other people are in foul trouble?

I might have asked this awhile ago but if you put a guy 3rd on the depth chart and only want him to play if someone gets hurt or fouls out what should you set him to? Mop up?

Also if you had to choose between having an upperclassmen backup both guard spots or an upperclassmen/frosh each backing up a spot, what would you do? I did the one guy backs up two spots last season and it seemed like I got killed against the press.

It means he'll only come out if he's in foul trouble.

I'd have the upperclassman backup both spots versus a tough opponent. Let the freshman play otherwise.

I never set a player at 'mopup', but I believe that if one of the other two players at that position gets hurt or in foul trouble, the other one will pick up extra minutes before the mopup would enter the game.  
  If you use the setting 'play backups more in a blowout', then I think the mopup will get more minutes as well

Depends on stamina, tempo.  If you are going slowdown I would have someone backup 2 spots.  On uptempo, you are going to get too tired for that to be effective so I'd play the freshman.