I was just wondering if anybody does this. I traditionally switch my players' fatigue settings for the conference tournament and beyond to give my better players more minutes, but as I've read more about WIS I feel like this might be a bad idea. 

What do we think? I see the side of the argument that says if you're winning don't mess with things, and if you're losing then who cares what you try, but I traditionally fall right into the middle area of this dilemma in that I am, for instance, the 4 seed in the B10 Wooden tournament and don't see how I advance past the first round without pulling some strings and trying to mix things up a bit.

The tougher the opponent, the more likely I am to adjust fatigue, so as I climb in the post season, I make changes accordingly. Also take the D into acount (press vs man vs zone). Also depends on the minutes he gives starters and reserves too. Lots of variables in the equation for me.