It's not easy to run FB at D1 unless you have an Elite program already. The types of players that work at D2 and D3 don't at D1 since most of your opponents are going to have speed, shooting, defense and rebounding everywhere. You need certain advantages/match-ups to help the break work, and those are really hard to come by at D1.
The worst part of the FB is that there is no slow down option, so...if you are building up a program you will suffer from not "stealing" those 2-3 games a year by running a slowdown, keeping the game close and praying the other team struggles. You tend to get run out of the building...
Another negative is that the opposite works well on you. Teams can play a slowdown which leads to less shot's taken which leads to less chances for you to run.
I've had alot of success at D2/D3 running the break, but DI is a different beast. It can and has been done, but it's just not easy :)