All else being equal, I would take a 50 DEF over a 99 SB at either post position in zone or m2m and it would be something of a tossup in the press. At SF I'd take the shot blocker in the zone, lean towards him slightly in the man, and go with the DEF guy in the press. Guards I'd probably take the defense, but it would be pretty close in anything other than press. FWIW, I think a lot of coaches massively undervalue SB. If you look at the differences between first- and second-tier defensive teams in D2 and D3, you'll find that they often have similar team defensive ratings but the most elite defenses are significantly better in SB.