Theoretically, was just wondering if you had heavy PF/C team (5-7 players) running the flex who had good LP ratings, how you would best utilize these guys? I don't think it would be a disadvantage, but in Hoops 101 it says flex is best used for teams with good speed, passing and perimeter.  Lets just say these guys are playing at D1 or D2 and their passing is average to good. 

Just thinking about some scenarios and stuff.
Wouldn't mind having some feedback or sitemail from anyone if that's cool.

no matter what - you don't want a SF that cant pass or handle the ball. If none of your PF/C have decent ball handling/passing ratings, then play the best at PF/C and sit the rest on the bench.  

In short, don't play any of those big guys at SF unless they are  versatile  for the position.