I think so. Here's what I think the difference is:
In the 2-3, I think the 1-2 only are used to only (or mostly) cover 3 point shots. This is why speedy guards in the 2-3 do a real good job stopping 3 points shots.
In the 3-2 the 1-2-3 cover 3 point shots and mid range jumpers. Speed is a little less important.
I used to think WHO took the shot was important but now I am not so sure.
At some point I want to take a look at my high ATH high LP guards and see how they do against zone defenses. I do now that my zone teams tend to do well against the 2 point shooting driving type guards but that might for other reasons (defensive setting, good defense, just high ath cores, low LP score on the offense).