Are we talking in hindsight? Are we looking for how to evaluate a player's statistics after they have played or are we talking about evaluating players based on their ratings and expected performance? I am sure there is some fully involved formula or theory about how a great defensive play saves a certain amount of runs, but I don't know what the formula is. Also, I am curious what people think regarding turning hits into outs while on defense vs. turning outs into hits while on offense. I am sure some would argue they are equal. Others may take one or the other side of the discussion. I would be interested in hearing those arguments.
Outside of the draft, I have rarely been in a situation where the guy that overplays a defensive position, but isn't a great hitter AND the guy that underplays the defensive position, but is a decent hitter are both available at the same price at the same time. Typically, the guy that can fake it at the defensive position and hit for 750+ OPS will get snatched up in free agency before the Rule 5 draft. Whereas, the guy that will offer the opportunity for 15+ plus plays and 7 less errors than the average replacement player at the position [but OPS's .625] is still available after Rule 5 for cheap.
Regardless of what the argument is regarding who the more valuable player is, I am taking the least expensive player because usually the difference is close to negligible.