My first instinct is such a game is actually to go uptempo, though I'm slowly learning that isn't always best in HD.
Here though, they foul the hell out of people, and you have a clear advantage in speed, ath, and relevant IQ. They play 12 guys, but not all 12 are good, so I'd try to maximize the number of minutes played by guys like
this.
Really though, emy is right. Forget the Hanover (tight game) and Cal Tech (horrible guard play) and just do what you do with Roanoke. It's working; don't over think it.