150 GS
1 Error
17 + plays

105 runs 201 hits 30 2b 1 3b 15 HR 72 RBI 30 SB

http://whatifsports.com/HBD/Pages/Popups/PlayerProfile.aspx?pid=4336083

Charlie Stone

Season 16...128 runs, 210 hits, 32 HR, 140 RBI, 25 SB, .318, 16+ plays, 45 doubles, 13 triples

12 errors though

Safe to say the extra 68 RBI made up for the potential runs given up through those 12 errors.

I found a better one pretty quickly by looking through the history of one of my leagues, so I'm assuming there are probably hundreds of better 3B seasons if you look through all of HBD.
In season 23, this guy hit .320/.401/.621 with 42 homers and 54 stolen bases. He had 16 plus plays and 0 minus plays.

He's had some other seasons with better fielding (21/0 +/- in season 25 for example) but slightly worse hitting, so take your pick as to which was his best all around.

http://whatifsports.com/HBD/Pages/Popups/PlayerProfile.aspx?pid=3822473

Me

Brooks Robinson?

Hardball Dynasty – Fantasy Baseball Sim Games - Player Profile: Victor Santiago

11+ plays, 4 errors.  41 2b, 41 HR, 140 RBI, 194 hits, 127 RS, and 34 SB.  1.101 OPS, .424 OBP.