Rather than follow the stats, you want to follow the defensive ratings for positions.
Stats like range factor can be distorted by other factors. Pitchers GB/FB tendencies will lead to more or less chances for your infielders and outfielders. Pitchers velocity ratings will lead to more or less strikeouts, which in turn leads to less or more balls in play and therefore less or more chances for your fielders.
In the end, defensive stats are merely a by-product of the defensive ratings modified by these other factors.