Mully two comments. First off, didn't tarek once run 500 sims at each level for the same two evenly matched teams? I tried to google it too see if I could find the results but could not find it.
Second, I one time played a season with all ten of my teams set to -4. The wins and losses didn't change real much, if I recall I got a few more boards, gave up a few more threes and at a higher %, maybe fouled a little bit more, defended two a little bit better. The % change from a my expected defense was in the 4% range - i.e. I defended the three 4% worse, say from 32% to 36% (which one could say was really a 12% change or 36/32*100).
I did decide I lost a few games as result, and quit the experiment b4 the national tournament for all my teams, my guess is vs the high end of d1 teams, the change would even be greater, but not that great, say from 32% to 40%. This was very much in line with what I recall seeing tarek report back to us when he actually ran the experiment.
I must admit, if this is about the change between 0 and -4 today, lower % on 2's, higher on 3's, fewer attempted 2's more attempted 3's, 1-2 extraboards, I'm ok with it. I don't want -4 to cause on averge 20% shooting from 2 and 66% shooting from 3 for example, as I want realistic box scores, and no games in real college basketball between 2 even teams results in 20% shooting from 2 or 66% from 3, based on the defensive settings.
I might consider making a more limited, maybe more controlled experiement with some of my teams if anyone is interested. It does take a little guesswork to determine the real results, as one really doesn't know what the results would be if I did play the 'right' defense instead of -4.
What would you or anyone else want to see in such an experment?