My team in Majors was the reason I came back to HBD. Detroit (I am a Tigers fan) was available and I had some unused credits so I said what the hell? The best pitcher on the team was and still is Midre Escuela.
Player Profile: Midre Escuela - Hardball Dynasty Baseball | WhatIfSports
Because I had him and his 60/24 Stamina/Dur I decided to try a full tandem team. Signed a bunch of very good pitchers with low Stamina that could pitch every 4th day for 3 or 4 innings. First year it went great. Won the WS and Escuela and a others were very good like a 3.10 ERA or so for Escuela. Year 2 something happened. Escuela's ERA and WHIP both ballooned terribly. I couldn't figure out what the hell was going on. At the halfway point his ERA was over 5.5....yikes. I noticed he was getting pounded later in his outings say inning 4 so I lowered the pitch counts from the default (60 I believe it was) down to 50. Since then his ERA has been below 3.00 the last two seasons, and his innings are actually up.
Now that is one guy and one situation but since then I always pay attention to under performing pitchers and if they start to show a pattern of getting knocked around late I will lower the PC by 10 or 15.