Defense will help/hurt your pitching. If you have guys getting + plays, they're taking hits off the board. Leads to less pitches required. Errors and - plays requires more pitches. So the guy you think should be able to give you 7 innings ends up giving you 6. And you have to build a bullpen capable of more work.
As a general rule, I want 85 across the board at SS and at least 85 range in CF. You can pick up a lot of + plays in LF with a 82/62 R/G that is essentially a failed CF. I sometimes skimp on D at 3B/RF because they get the least chances in the IF/OF, respectively.