I'd run whatever is your favorite, whatever you're best at, or if you understand your own recruiting tendencies I'd go with whatever you recruit best for. And focus on your long term ideas. I would NOT pick sets based on your current situation for this season alone. Because you'll suck the first season of a rebuild anyway.
If you're going to continue to keep walk ons each season, zone is a good choice. If you're going to fill your roster next season with all those extra resources, go press. If you like to focus on one on one matchups when game planning, go man. And then pick your offense based off similar thought process. I'm not sure this part matters but if you're in a full human conference, be aware if it's overwhelmed with a certain set. If everybody plays fastbreak/press, you'll be in constant battles for the recruits with green ATH/SPD/DEF/ST
wow that was long winded