None whatsoever, the game isn't nearly that sophisticated. Development is based on games played (whether the player starts or comes off the bench/bullpen). My elite prospects come off the bench for the entire time they're in the minor leagues to reduce the chance of major injury before hitting the majors. Position players probably get 200 PA's in a season, pitchers (including starters who I use as relievers) get ~70 IP. They always hit their potential. It's a no-brainer strategy IMO. I can get full potential while reducing the chance of a freak injury before they make their ML debut.
Only downside is the prospect's teams chances are reduced at making playoffs and getting in a few extra games of development (unless playoff games don't matter, haven't been able to find any info either way on that one).