Oh wait, I meant yes

That's my final answer, Regis.
Just tested it, using the Naps' Ed Klepfer.
RL 5.1 IP/G
As starter:
21 pitches, in-game fatigue 98%
52 pitches, in-game fatigue 91%
As reliever (brought in after one batter):
20 pitches, 96%
35 pitches, 89%
54 pitches, 61%
Tell those Athletics to take some pitches, btown!