1. You are on the right track. It depends what kind of defense he's in, regarding how you go about that. If your opponent plays man defense, and has a weak defender in the starting lineup, it's pretty straight forward. Up distribution at the spot you expect that guy to play, or put your best (appropriate for position) offensive player there, or some combination. Don't go overboard, upping distribution too much for a player limits his efficiency. I always stay under 20%, fwiw. Your opponent can always move that guy around if his team is flexible enough, so it becomes a bit of a chess match. When I'm gameplanning for real, I usually look back at the last 5-7 starting lineups he's thrown out there. If they are the same, I'm reasonably confident I know where he'll be.
Attacking zone and press weak spots are a little less straight-forward. In zone, pay attention to what he normally plays, 2-3 or 3-2. If 2-3, he'll be more open to jump shots and perimeter scoring, especially if the weak defender is a guard. In a 3-2, you can exploit the paint, and the boards.
Against the press, he's always double teaming, and there's no way (that I can tell) to determine who the "help" defender is. I like to attack the weak defender by position as with man, but for a different reason. If I go that route, I'm trying to get him in foul trouble, and start the "fatigue cascade" that can ripple through his team.
2. You can play any guy anywhere on the floor, but each position is weighted a little differently regarding what attributes are important, and how effective and efficient he'll be. In your hypothetical, if you have a good scoring SF, and playing a team playing man defense with a weak PF, you can absolutely move him over to exploit that match-up. But realize that you're changing your own defensive assignments doing that. Some PF are too slow, and can get burned if you move them to the wing, even if they have good defensive ratings. Likewise, if your SF is not a strong rebounder, be aware that you are also giving up ground on rebounds.
3/7/2017 1:39 PM (edited)